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The Cause of Rosacea

It is now believed that the primary underlying cause of rosacea has nothing to do with Helicobacter pylori or what a patient eats.

Demodex may be an exacerbating factor, but not the cause.

We still don’t know for sure what causes rosacea, but it’s probably a disturbed control of inflammation — the innate immune system bactericidal peptides may be proteolytically cleaved into irritating compounds.

Interestingly, the drugs that make rosacea better are those that inhibit matrix metalloproteinases (MMPs), such as doxycycline, however these are not a long-term solution.


Author: Peter Wilson.

Reviewed: Sunday, January 20, 2008.


Further Information: The Cause of Rosacea : Rosacea Cooling — New in Rosacea Therapy for 2008 : Changes to Rosacea Cleansers in 2008 : Association Between Rosacea Rhinophyma and Increased Mast Cells :




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